The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by

Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...

to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of

biology Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary i ...

biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...

. The prize was established at the bequest of S. Gross Horwitz and is named to honor his mother, Louisa Gross Horwitz, the daughter of trauma surgeon

Samuel D. Gross Samuel David Gross (July 8, 1805 – May 6, 1884) was an American academic trauma surgeon. Surgeon biographer Isaac Minis Hays called Gross "The Nestor of American Surgery." He is immortalized in Thomas Eakins' ''The Gross Clinic'' (1875), a ...

. The prize was first awarded in 1967. As of October 2018, 51 (50%) of the 101 prize recipients have subsequently been awarded the

Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accord ...

(40) or

Chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...

(11). It is regarded as one of the important precursors of a future Nobel Prize award.

Recipients

*1967

Luis Leloir Luis Federico Leloir (September 6, 1906 – December 2, 1987) was an Argentine physician and biochemist who received the 1970 Nobel Prize in Chemistry for his discovery of the metabolic pathways in lactose. Although born in France, Leloir r ...

(1970 Chemistry) *1968

Har Gobind Khorana Har Gobind Khorana (9 January 1922 – 9 November 2011) was an Indian American biochemist. While on the faculty of the University of Wisconsin–Madison, he shared the 1968 Nobel Prize for Physiology or Medicine with Marshall W. Nirenberg and ...

(1968 Physiology or Medicine),

Marshall Warren Nirenberg Marshall Warren Nirenberg (April 10, 1927 – January 15, 2010) was an American biochemist and geneticist. He shared a Nobel Prize in Physiology or Medicine in 1968 with Har Gobind Khorana and Robert W. Holley for "breaking the genetic code" a ...

(1968 Physiology or Medicine) *1969

Max Delbrück Max Ludwig Henning Delbrück (; September 4, 1906 – March 9, 1981) was a German–American biophysicist who participated in launching the molecular biology research program in the late 1930s. He stimulated physical science, physical scientist ...

(1969 Physiology or Medicine), Salvador E. Luria (1969 Physiology or Medicine) *1970

Albert Claude Albert Claude (; 24 August 1899 – 22 May 1983) was a Belgian-American cell biologist and medical doctor who shared the Nobel Prize in Physiology or Medicine in 1974 with Christian de Duve and George Emil Palade. His elementary education s ...

(1974 Physiology or Medicine), George E. Palade (1974 Physiology or Medicine), Keith R. Porter *1971 Hugh E. Huxley *1972 Stephen W. Kuffler *1973 Renato Dulbecco (1975 Physiology or Medicine),

Harry Eagle Harry Eagle (July 13, 1905 – June 21, 1992) was an American physician and pathologist. He was born in New York City then studied, and later worked, at Johns Hopkins University before moving on to the National Institutes of Health. From 1961 to 1 ...

Theodore T. Puck Theodore Thomas Puck (September 24, 1916 – November 6, 2005) was an American geneticist born in Chicago, Illinois. He attended Chicago public schools and obtained his bachelors, masters, and doctoral degree from the University of Chicago. His ...

*1974

Boris Ephrussi Boris Ephrussi (russian: Борис Самойлович Эфрусси; 9 May 1901 – 2 May 1979), Professor of Genetics at the University of Paris, was a Russo- French geneticist. Boris was born on 9 May 1901 into a Jewish family. His father, ...

*1975 K. Sune D. Bergstrom (1982 Physiology or Medicine),

Bengt Samuelsson Bengt Ingemar Samuelsson (born 21 May 1934) is a Swedish biochemist. He shared with Sune K. Bergström and John R. Vane the 1982 Nobel Prize for Physiology or Medicine for discoveries concerning prostaglandins and related substances. Education a ...

(1982 Physiology or Medicine) *1976 Seymour Benzer,

Charles Yanofsky Charles Yanofsky (April 17, 1925 – March 16, 2018) was an American geneticist on the faculty of Stanford University who contributed to the establishment of the one gene-one enzyme hypothesis and discovered attenuation, a riboswitch mechanis ...

*1977

Michael Heidelberger Michael Heidelberger (April 29, 1888 – June 25, 1991) was an American immunologist, often regarded as the father of modern immunology. He and Oswald Avery showed that the polysaccharides of pneumococcus are antigens, enabling him to show tha ...

Elvin A. Kabat Elvin Abraham Kabat (September 1, 1914 – June 16, 2000) was an American biomedical scientist and one of the founding fathers of modern quantitative immunochemistry. Kabat was awarded the Louisa Gross Horwitz Prize from Columbia University in 1 ...

, Henry G. Kunkel *1978

David Hubel David Hunter Hubel (February 27, 1926 – September 22, 2013) was a Canadian American neurophysiologist noted for his studies of the structure and function of the visual cortex. He was co-recipient with Torsten Wiesel of the 1981 Nobel Priz ...

(1981 Physiology of Medicine),

Vernon Mountcastle Vernon Benjamin Mountcastle (July 15, 1918 – January 11, 2015) was an American neurophysiologist and Professor Emeritus of Neuroscience at Johns Hopkins University. He discovered and characterized the columnar organization of the cerebral co ...

Torsten Wiesel Torsten Nils Wiesel (born 3 June 1924) is a Swedish neurophysiologist. With David H. Hubel, he received the 1981 Nobel Prize in Physiology or Medicine, for their discoveries concerning information processing in the visual system; the prize was ...

(1981 Physiology or Medicine) *1979

Walter Gilbert Walter Gilbert (born March 21, 1932) is an American biochemist, physicist, molecular biology pioneer, and Nobel laureate. Education and early life Walter Gilbert was born in Boston, Massachusetts, on March 21, 1932, the son of Emma (Cohen), a ...

(1980 Chemistry),

Frederick Sanger Frederick Sanger (; 13 August 1918 – 19 November 2013) was an English biochemist who received the Nobel Prize in Chemistry twice. He won the 1958 Chemistry Prize for determining the amino acid sequence of insulin and numerous other p ...

(1980 Chemistry) *1980 César Milstein (1984 Physiology or Medicine) *1981 Aaron Klug (1982 Chemistry) *1982 Barbara McClintock (1983 Physiology or Medicine), Susumu Tonegawa (1987 Physiology or Medicine) *1983 Stanley Cohen (1986 Physiology or Medicine),

Viktor Hamburger Viktor Hamburger (July 9, 1900 – June 12, 2001)Garland E. AllenViktor Hamburger, 1900–2001. National Academy of Sciences Biographical Memoirs, 2015, 39 pp. was a German-American professor and embryologist. His collaboration with neuroscie ...

Rita Levi-Montalcini Rita Levi-Montalcini (, ; 22 April 1909 – 30 December 2012) was an Italian Nobel laureate, honored for her work in neurobiology. She was awarded the 1986 Nobel Prize in Physiology or Medicine jointly with colleague Stanley Cohen for th ...

(1986 Physiology or Medicine) *1984 Michael S. Brown (1985 Physiology or Medicine), Joseph L. Goldstein (1985 Physiology or Medicine) *1985

Donald D. Brown Donald David Brown (December 30, 1931 – May 31, 2023) was an American biologist and one of the founders of molecular embryology. Early life Brown was born in Cincinnati, Ohio to Dr. Albert Brown, an Ophthalmology, ophthalmologist, and Lo ...

Mark Ptashne Mark Ptashne (born June 5, 1940, in Chicago) is a molecular biologist. He is the Ludwig Chair of Molecular Biology at Memorial Sloan–Kettering Cancer Center in New York City. Ptashne grew up in Chicago. He earned his undergraduate degree at Re ...

*1986

Erwin Neher Erwin Neher (; ; born 20 March 1944) is a German biophysicist, specializing in the field of cell physiology. For significant contribution in the field, in 1991 he was awarded, along with Bert Sakmann, the Nobel Prize in Physiology or Medicine for ...

(1991 Physiology or Medicine),

Bert Sakmann Bert Sakmann (; born 12 June 1942) is a German cell physiologist. He shared the Nobel Prize in Physiology or Medicine with Erwin Neher in 1991 for their work on "the function of single ion channels in cells," and the invention of the patch cla ...

(1991 Physiology or Medicine) *1987

Günter Blobel Günter Blobel (; May 21, 1936 – February 18, 2018) was a Silesian German and American biologist and 1999 Nobel Prize laureate in Physiology for the discovery that proteins have intrinsic signals that govern their transport and localization in ...

(1999 Physiology or Medicine) *1988

Thomas R. Cech Thomas Robert Cech (born December 8, 1947) is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman, for their discovery of the catalytic properties of RNA. Cech discovered that RNA could itself cut strands of RNA, ...

(1989 Chemistry),

Philip A. Sharp Phillip Allen Sharp (born June 6, 1944) is an American geneticist and Molecular biology, molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for "the discovery th ...

(1993 Physiology or Medicine) *1989 Alfred G. Gilman (1994 Physiology or Medicine),

Edwin G. Krebs Edwin Gerhard Krebs (June 6, 1918 – December 21, 2009) was an American biochemist. He received the Albert Lasker Award for Basic Medical Research and the Louisa Gross Horwitz Prize of Columbia University in 1989 together with Alfred Gilman and ...

(1994 Physiology or Medicine) *1990 Stephen C. Harrison, Michael G. Rossmann, Don C. Wiley *1991

Richard R. Ernst Richard Robert Ernst (14 August 1933 – 4 June 2021) was a Swiss physical chemist and Nobel Laureate. Ernst was awarded the Nobel Prize in Chemistry in 1991 for his contributions towards the development of Fourier transform nuclear magnetic re ...

(1991 Chemistry),

Kurt Wüthrich Kurt Wüthrich (born 4 October 1938 in Aarberg, Canton of Bern) is a Swiss chemist/biophysicist and Nobel Chemistry laureate, known for developing nuclear magnetic resonance (NMR) methods for studying biological macromolecules. Education and ...

(2001 Chemistry) *1992

Christiane Nüsslein-Volhard Christiane (Janni) Nüsslein-Volhard (; born 20 October 1942) is a German developmental biologist and a 1995 Nobel Prize in Physiology or Medicine laureate. She is the only woman from Germany to have received a Nobel Prize in the sciences. N� ...

(1995 Physiology or Medicine),

Edward B. Lewis Edward Butts Lewis (May 20, 1918 – July 21, 2004) was an American geneticist, a corecipient of the 1995 Nobel Prize in Physiology or Medicine. He helped to found the field of evolutionary developmental biology. Early life Lewis was born in Wi ...

(1995 Physiology or Medicine) *1993 Nicole Marthe Le Douarin,

Donald Metcalf Donald Metcalf AC FRS FAA (26 February 1929 – 15 December 2014) was an Australian medical researcher who spent most of his career at the Walter and Eliza Hall Institute of Medical Research in Melbourne. In 1954 he received the Carden ...

*1994 Philippa Marrack, John W. Kappler *1995

Leland H. Hartwell Leland Harrison (Lee) Hartwell (born October 30, 1939 in Los Angeles, California) is former president and director of the Fred Hutchinson Cancer Research Center in Seattle, Washington. He shared the 2001 Nobel Prize in Physiology or Medicine wit ...

(2001 Physiology or Medicine) *1996 Clay M. Armstrong, Bertil Hille *1997 Stanley B. Prusiner (1997 Physiology or Medicine) *1998 Arnold J. Levine,

Bert Vogelstein Bert Vogelstein (born 1949) is director of the Ludwig Center, Clayton Professor of Oncology and Pathology and a Howard Hughes Medical Institute investigator at The Johns Hopkins Medical School and Sidney Kimmel Comprehensive Cancer Center. A pi ...

*1999 Pierre Chambon, Robert Roeder,

Robert Tjian Robert Tjian (; born 1949) is a Hong Kong-born American biochemist best known for his work on eukaryotic transcription. He is currently Professor of Biochemistry and Molecular Biology at the University of California, Berkeley and an Investigator ...

*2000

H. Robert Horvitz Howard Robert Horvitz ForMemRS NAS AAA&S APS NAM (born May 8, 1947) is an American biologist best known for his research on the nematode worm ''Caenorhabditis elegans'', for which he was awarded the 2002 Nobel Prize in Physiology or Medicine, t ...

(2002 Physiology or Medicine), Stanley J. Korsmeyer *2001

Avram Hershko Avram Hershko ( he, אברהם הרשקו, Avraham Hershko, hu, Herskó Ferenc Ábrahám; born December 31, 1937) is a Hungarian-Israeli biochemist who received the Nobel Prize in Chemistry in 2004. Biography He was born Herskó Ferenc in Karc ...

(2004 Chemistry),

Alexander Varshavsky Alexander Jacob Varshavsky (russian: link=no, Александр Яковлевич Варшавский; born 8 November 1946) is a Russian-American biochemist, noted for his discovery of the N-end rule of ubiquitination. A native of Moscow, he ...

*2002 James E. Rothman (2013 Physiology or Medicine), Randy W. Schekman (2013 Physiology or Medicine) *2003

Roderick MacKinnon Roderick MacKinnon (born February 19, 1956) is an American biophysicist, neuroscientist, and businessman. He is a professor of Molecular Neurobiology and Biophysics at Rockefeller University who won the Nobel Prize in Chemistry together with Peter ...

(2003 Chemistry) *2004 Tony Hunter, Tony Pawson *2005

Ada Yonath Ada E. Yonath ( he, עדה יונת, ; born 22 June 1939) is an Israeli crystallographer best known for her pioneering work on the structure of ribosomes. She is the current director of the Helen and Milton A. Kimmelman Center for Biomolecular ...

(2009 Chemistry) *2006

Roger D. Kornberg Roger David Kornberg (born April 24, 1947) is an American biochemist and professor of structural biology at Stanford University School of Medicine. Kornberg was awarded the Nobel Prize in Chemistry in 2006 for his studies of the process by which ...

(2006 Chemistry) *2007 Joseph G. Gall, Elizabeth H. Blackburn (2009 Physiology or Medicine),

Carol W. Greider Carolyn Widney Greider (born April 15, 1961) is an American molecular biologist and Nobel laureate. She joined the University of California, Santa Cruz as a Distinguished Professor in the department of molecular, cell, and developmental biology ...

(2009 Physiology or Medicine) *2008

F. Ulrich Hartl Franz-Ulrich Hartl (born 10 March 1957) is a German biochemist and Managing Director of the Max Planck Institute of Biochemistry. He is known for his pioneering work in the field of protein-mediated protein folding and is a recipient of the 201 ...

, Arthur Horwich and Honorary Horwitz Prize to Rosalind Franklin *2009 Victor R. Ambros,

Gary Ruvkun Gary Bruce Ruvkun (born March 1952, Berkeley, California) is an American molecular biologist at Massachusetts General Hospital and professor of genetics at Harvard Medical School in Boston. Ruvkun discovered the mechanism by which ''lin-4'', th ...

*2010 Thomas J. Kelly,

Bruce Stillman Bruce William Stillman, AO, FAA, FRS (born 16 October 1953, in Melbourne, Australia) is a biochemist and cancer researcher who has served as the Director of Cold Spring Harbor Laboratory (CSHL) since 1994 and President since 2003. He also serv ...

*2011 Jeffrey C. Hall (2017 Physiology or Medicine),

Michael Rosbash Michael Morris Rosbash (born March 7, 1944) is an American geneticist and chronobiologist. Rosbash is a professor and researcher at Brandeis University and investigator at the Howard Hughes Medical Institute. Rosbash's research group cloned the ...

(2017 Physiology or Medicine),

Michael W. Young Michael Warren Young (born March 28, 1949) is an American biologist and geneticist. He has dedicated over three decades to research studying genetically controlled patterns of sleep and wakefulness within ''Drosophila melanogaster''. At Rock ...

(2017 Physiology or Medicine) *2012

Richard Losick Richard Marc Losick ( ; born 1943) is an American molecular biologist. He is the Maria Moors Cabot Professor of Biology at Harvard University, a Howard Hughes Medical Institute Professor. He is especially noted for his investigations of endospore f ...

, Joe Lutkenhaus,

Lucy Shapiro Lucy Shapiro (born July 16, 1940, New York City) is an American developmental biologist. She is a professor of Developmental Biology at the Stanford University School of Medicine. She is the Virginia and D.K. Ludwig Professor of Cancer Res ...

*2013 Edvard I. Moser (2014 Physiology or Medicine),

May-Britt Moser May-Britt Moser (born 4 January 1963) is a Norwegian psychologist and neuroscientist, who is a Professor of Psychology and Neuroscience at the Norwegian University of Science and Technology (NTNU). She and her then-husband, Edvard Moser, share ...

(2014 Physiology or Medicine), John O’Keefe (2014 Physiology or Medicine) *2014

James P. Allison James Patrick Allison (born August 7, 1948) is an American immunologist and Nobel laureate who holds the position of professor and chair of immunology and executive director of immunotherapy platform at the MD Anderson Cancer Center at the Uni ...

(2018 Physiology or Medicine) *2015 S. Lawrence Zipursky *2016

Howard Cedar Howard Chaim Cedar (Hebrew: חיים סידר; born January 12, 1943) is an Israeli American biochemist who works on DNA methylation, a mechanism that turns genes on and off. Biography Howard Chaim Cedar was born in the United States. He rece ...

, Aharon Razin, *2017

Jeffrey I. Gordon Jeffrey I. Gordon (born 1947) is a biologist and the Dr. Robert J. Glaser Distinguished University Professor and Director of the Center for Genome Sciences and Systems Biology at Washington University in St. Louis. He is internationally known f ...

*2018 Pierre Chambon,

Ronald M. Evans Ronald Mark Evans (born April 17, 1949 in Los Angeles, California) is an American Biologist, Professor and Head of the Salk’s Gene Expression Laboratory, and the March of Dimes Chair in Molecular and Developmental Biology at the Salk Institute fo ...

Bert O’Malley Bert W. O’Malley is the Tom Thompson Distinguished Service Professor of Molecular and Cellular Biology and Chancellor at Baylor College of Medicine. A native of Pittsburgh, he has a bachelor's degree from the University of Pittsburgh (A&S 1959) a ...

*2019 Lewis C. Cantley,

David M. Sabatini David M. Sabatini (born January 27, 1968) is an American scientist and a former professor of biology at the Massachusetts Institute of Technology. From 2002 to 2021, he was a member of the Whitehead Institute for Biomedical Research. He was also ...

, Peter K. Vogt *2020 Robert Fettiplace, James Hudspeth, Christine Petit *2021

Katalin Karikó Katalin Karikó ( hu, Karikó Katalin, ; born 17 January 1955) is a Hungarian-American biochemist who specializes in RNA-mediated mechanisms. Her research has been the development of in vitro- transcribed mRNA for protein therapies. She co-fo ...

Drew Weissman Drew Weissman (born 1959) is an American physician-scientist best known for his contributions to RNA biology. His work helped enable development of effective mRNA vaccines, the best known of which are those for COVID-19 produced by BioNTech/P ...

*2022

Karl Deisseroth Karl Alexander Deisseroth (born November 18, 1971) is an American scientist. He is the D.H. Chen Professor of Bioengineering and of psychiatry and behavioral sciences at Stanford University. He is known for creating and developing the technolo ...

Peter Hegemann Peter Hegemann (born 11 December 1954) is a Hertie Senior Research Chair for Neurosciences and a Professor of Experimental Biophysics at the Department of Biology, Faculty of Life Sciences, Humboldt University of Berlin, Germany. He is known ...

Gero Miesenböck Gero Andreas Miesenböck (born 15 July 1965) is an Austrian scientist. He is currently Waynflete Professor of Physiology and Director of the Centre for Neural Circuits and Behaviour (CNCB) at the University of Oxford and a fellow of Magdalen ...

Laureates 2022
/ref>

Notes

External links

* {{DEFAULTSORT:Horwitz Prize Awards established in 1967 Biology awards Medicine awards Awards and prizes of Columbia University 1967 establishments in New York City Biochemistry awards

Recipients

See also

Notes

External links